Atorvastatin pleiotropic benefits

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Atorvastatin pleiotropic benefits
The present study evaluated whether atorvastatin, a potent statin, ameliorates the
serum markers of pleiotropic effects, with a focus on dose-dependency.Many of these pleiotropic effects are mediated by inhibition of isoprenoids, which
… between the various statins, with the synthetic compounds atorvastatin and …Keywords: Coronary artery disease, pleiotropic effects, rosuvastatin, statins …
The subjects received either atorvastatin 10 mg/day or placebo and their total …Pleiotropic effects of statins include improvement of endothelial dysfunction, ….
Similar effects of atorvastatin, simvastatin and pravastatin on thrombogenic and …12 Mar 2013 … Statins have pleiotropic effects—that is, they are simultaneously … was
cholesterol lowering greater in the atorvastatin limb (see below), but …effects. Understanding the pleiotropic effects of statins is important to optimize
their use in treatment … atorvastatin have shown no impact of statin therapy on.The relative contributions of statin pleiotropy to clinical outcomes, however,
remain …. Effects of atorvastatin on early recurrent ischemic events in acute
coronary …Key Words: Statins · Pleiotropic effects · Atherosclerosis. INTRODUCTION …. terol
, followed by simvastatin and atorvastatin (maximal increase 9.6% vs 6.8% vs …10 Sep 2004 … pleiotropic effects shown by statin therapy offer many advantages over the ….
simvastatin,[44, 45] lovastatin[45] and atorvastatin[45] which may.The pleiotropic effects of statins do not seem to contribute an additional …
Pravastatin or Atorvastatin Evaluation and Infection Therapy–Thrombolysis In …26 Jan 2017 … Endothelial progenitor cells: Exploring the pleiotropic effects of statins. …
Similarly, in ACS patients' intensive statin therapy with atorvastatin 80 …22 Jan 2013 … It has been proposed that these so-called pleiotropic effects [2] contribute …. No
difference was found between simvastatin or atorvastatin for all …9 May 2018 … We found that patients who are aware of the pleiotropic effects of … defined as
high-intensity statin therapy, while atorvastatin 10 and 20 mg, …Pleiotropic Effects of Atorvastatin in Experimental Sepsis: Preservation of β1-
Adrenoreceptor Signaling in the Heart. Coldewey, Sina M. *; Thiemermann, …13 Sep 2016 … referred to as “pleiotropic” effects. … familial hypercholesterolemia, the effects of
statins … Rosuvastatin Versus Atorvastatin) study (4), which.Abstract: To study pleiotropic effects of atorvastatin during 8-week therapy of
metabolic syndrome and estimate their relationship with dynamics of quality…Increased oxidative stress, a common feature in chronic heart failure, has been
associated with inflammation, endothelial dysfunction, and extracellular matrix …28 Aug 2018 … Aim: To study the relationship of atorvastatin pleiotropic effects depending on the
doses used during the 24-week therapy in patients with …The present study analyzed the effect ofincreasing the atorvastatin dose to 80 …
Statins also have so-called pleiotropic effects, which improve endothelial …4 Dec 2017 … In our study, we compared the short-term effects of high (80 mg) vs … Marzilli M.
Pleiotropic effects of statins: evidence for benefits beyond …

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