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Oxymorphone (brand names Opana, Numorphan, Numorphone), also known as 14-hydroxydihydromorphinone, is a powerful semi-synthetic opioid analgesic (painkiller) first developed in Germany in 1914, patented buprenorphine in the USA by Endo Pharmaceuticals in 1955 and introduced to the United States market in January 1959 and other .

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