Theophylline narrow therapeutic range

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Theophylline narrow therapeutic range
Theophylline, also known as 1,3-dimethylxanthine, is a methylxanthine drug
used in therapy for … The use of theophylline is complicated by its interaction with
various drugs and by the fact that it has a narrow therapeutic window. Its use
must …7 Jan 2016 … Theophylline (1,3-dimethylxanthins) can indirectly stimulate both β1 and β2 …
Medication, diet, and underlying diseases can alter its narrow therapeutic
window. Adverse … Therapeutic serum levels range from 10-20 mcg/mL.19 Dec 2013 … It also lets the clinician know when the dose of theophylline can be adjusted
within this range to achieve a therapeutic effect if the patient is still …These studies, the narrow therapeutic range of the drug, the frequency of side
effects and interactions with common drugs, and individual variation in clearance
 …When drug monitoring is performed, the therapeutic range that has been
established should be used only as a guide. However, theophylline has a narrow
 …8 Nov 2017 … One reason may be that it has a narrow therapeutic index. Fortunately,
theophylline serum levels correlate well with both therapeutic and toxic …Drugs like Theophylline have a narrow range of therapeutic index. Potential
toxicity occur above serum concentration of 20 mg/L. Serious toxicities could
result …27 Apr 2014 … odmerjanja. Key words: theophylline pharmacokinetics; narrow therapeutic range
; serum level measurements; individualized dosage schedule.29 May 2018 … Drugs with a narrow therapeutic index (where therapeutic drug levels do not
differ … Example: Theophylline in patients with chronic obstructive …Narrow Therapeutic Index Drugs Have Low … for drugs with a Narrow
Therapeutic Index. (NTI)… … Tacrolimus, Theophylline, Warfarin; adds others
such as.(4) Medications with a narrow therapeutic index, such as theophylline, require a
heightened level of attention when prescribed. A study by Aitken and Marten, …8 Jun 2015 … To determine the concentration of theophylline or caffeine in the blood to
establish an appropriate dose and to maintain a therapeutic level.ABSTRACT Dose-dependency in theophylline pharmacokinetics and protein
binding character- istics was ….. theophylline has a narrow therapeutic margin
and.theophylline has a rather narrow therapeutic window, dose adjustment might be
… methylprednisolone, and prednisone) do not affect theophylline kinetics.14 Sep 2015 … A tool for monitoring drugs with narrow therapeutic window. … high levels. d)
Theophylline: This drug has a narrow therapeutic index and timing …23/9:15 AM-3:30 PM / Area K (Hall A-B2, Ground Level) – San Diego Convention
Center … Theophylline has a narrow clinical therapeutic index of 1 to 1.5.24 Mar 1994 … Introduction. Bronchodilation is the main effect of theophylline in the treatment of
patients with chronic … The reason is a narrow therapeutic range, a relatively
short interindividually varying half-life, absorption differences and.Some drugs have a narrow therapeutic index, which means that there is only a …
Therapeutic drug monitoring can also be useful when changes are made to …
Pre-dose. 5 – 15 microgram/L. 3. Theophylline. SST. Peak levels – 6 hours after.The established therapeutic range should be used as a guide only, due to
theophylline's narrow therapeutic index and daily variations in plasma
theophylline …